Functional imaging in schizencephaly using [18F]fluoro-2-deoxy-d-glucose positron emission tomography (FDG-PET) and single photon emission computed tomography with technetium-99m-hexamethyl-propyleneamine oxime (HMPAO-SPECT)

Abstract We analyzed interictal [18F]fluoro-2-deoxy-d-glucose positron emission tomography (FGD-PET) and single photon emission computed tomography with technetium-99m-hexamethyl-propyleneamine oxime (HMPAO-SPECT) in a 23-year-old female with schizencephaly. She had epilepsy and mild left hemiparesi... Ausführliche Beschreibung

1. Person: Morioka, T.
Weitere Personen: Nishio, Shunji; Sasaki, Masayuki; Yoshida, Tsuyoshi; Kuwabara, Yasuo; Nagamatsu, Tazuko; Fukui, Masashi
Quelle: in Neurosurgical review Vol. 22 (1999), p. 99-101
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Format: Online-Artikel
Genre: Key words Schizencephaly, [18F]Fluoro-2-deoxy-d-glucose positron emission tomography (FGD-PET), Single photon emission computed tomography with technetium-99m-hexamethyl-propyleneamine oxime (HMPAO-SPECT)
Sprache: English
Veröffentlicht: 1999
Beschreibung: Online-Ressource
Online Zugang: Online
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Anmerkung: Copyright: Copyright 1999 Springer-Verlag Heidelberg
Zusammenfassung: Abstract We analyzed interictal [18F]fluoro-2-deoxy-d-glucose positron emission tomography (FGD-PET) and single photon emission computed tomography with technetium-99m-hexamethyl-propyleneamine oxime (HMPAO-SPECT) in a 23-year-old female with schizencephaly. She had epilepsy and mild left hemiparesis, but was otherwise developmentally normal. We found the glucose metabolism and perfusion of the wall of the schizencephalic cleft to be identical to those of normal cerebral cortex. The wall of the transcerebral clefts, which were observed to be lined by abnormally organized gray matter as a result of a migration disorder, demonstrated gray matter metabolic activity and perfusion. FDG-PET and HMPAO-SPECT were thus found to be a useful complement to magnetic resonance imaging for evaluating schizencephaly.
ISSN: 1437-2320

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