Malignant myoepithelioma of the breast metastasizing to the jaw

Abstract  A breast tumor in a 52-year-old female was interpreted as a malignant myoepithelioma based on morphological and immunohistochemical studies. The tumor consisted of elongated cells with clear cytoplasm and lacked glandular components. The tumor cells were stained positively for keratin, S... Ausführliche Beschreibung

1. Person: Shiraishi, T.
Weitere Personen: Nakayama, Tsuyoshi; Fukutome, Kazuo; Watanabe, Masatoshi; Murata, Tetsuya
Quelle: in Virchows Archiv : official journal of the European Society of Pathology Vol. 435 (1999), p. 520-523
Weitere Artikel
Format: Online-Artikel
Genre: Key words Breast neoplasms, Malignant myoepithelioma, Metastasis, Immunohistochemistry
Sprache: English
Veröffentlicht: 1999
Beschreibung: Online-Ressource
Online Zugang: Online
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Anmerkung: Copyright: Copyright 1999 Springer-Verlag Berlin Heidelberg
Zusammenfassung: Abstract  A breast tumor in a 52-year-old female was interpreted as a malignant myoepithelioma based on morphological and immunohistochemical studies. The tumor consisted of elongated cells with clear cytoplasm and lacked glandular components. The tumor cells were stained positively for keratin, S-100 protein, glial fibrillary acidic protein (GFAP) and muscle-specific actin. Distant metastasis in the right jaw developed 8 years after the initial surgery and the metastatic deposit showed a similar morphology and immunoreactivity. Myoepithelial tumors are generally considered as benign or low-grade lesions and distant metastasis has been rarely documented. The present case presents the possibility of delayed occurrence of distant metastasis in myoepithelial tumor of the breast.
ISSN: 1432-2307

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