Crystallization of the Macromolecular Complex Transthyretin-Retinol-binding Protein

Single crystals of the macromolecular complex transthyretin-retinol-binding protein have been obtained. Transthyretin is a carrier of the hormone tryroxine in plasma whereas retinol-binding protein is the specific transporter of the alcohol form of the vitamin A in the same medium. This macromolecul... Ausführliche Beschreibung

1. Person: Monaco, H.L.
Weitere Personen: Mancia, F.; Rizzi, M.; Coda, A.
Quelle: in Journal of Molecular Biology Vol. 244, No. 1 (1994), p. 110-113
Weitere Artikel
Format: Online-Artikel
Genre: transthyretin, retinol-binding protein, crystallization, X-ray diffraction
Sprache: English
Veröffentlicht: 1994
Beschreibung: Online-Ressource
Online Zugang: Online
Volltext
Tags: Hinzufügen
Keine Tags. Fügen Sie den ersten Tag hinzu!
Anmerkung: Copyright: Copyright (c) 2007 Elsevier Ltd
LEADER 02418nma a2200457 c 4500
001 NLEJ185627617
003 DE-601
005 20151015030043.0
007 cr uuu---uuuuu
008 070506s1994 000 0 eng d
016 7 |a 1355192-9  |2 DE-600 
024 8 |a S0022-2836(84)71708-6 
035 |a (DE-599)GBVNLZ185627617 
040 |b ger  |c GBVCP 
041 0 |a eng 
084 |a sdj  |2 natliz 
245 0 0 |a Crystallization of the Macromolecular Complex Transthyretin-Retinol-binding Protein  |h Elektronische Ressource 
300 |a Online-Ressource 
500 |a Copyright: Copyright (c) 2007 Elsevier Ltd 
520 |a Single crystals of the macromolecular complex transthyretin-retinol-binding protein have been obtained. Transthyretin is a carrier of the hormone tryroxine in plasma whereas retinol-binding protein is the specific transporter of the alcohol form of the vitamin A in the same medium. This macromolecular complex is found under physiological conditions in plasma and is believed to play an important physiological role. The complex can formed in vitro by proteins purified from different species. Our crystals are grown with chicken retinol-binding protein complexed to human transthyretin. They are grown by equilibrium dialysis versus 2.3 M ammonium sulphate, 3% ethylene glycol buffered with 0.1 M succinate (pH 5.5). Their space group is I222(or I 2"12"12"1) with unit cell parameters a = 222.4 A, b = 163.4 A and c = 55.5 A. Using a conventional X-ray source, we have collected a complete data set of the crystals to a nominal resolution of 3.1 A 
533 |a Online edition  |f Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 ; 041023-8 
655 7 |a transthyretin  |2 gnd 
655 7 |a retinol-binding protein  |2 gnd 
655 7 |a crystallization  |2 gnd 
655 7 |a X-ray diffraction  |2 gnd 
689 0 0 |a transthyretin 
689 0 1 |a retinol-binding protein 
689 0 2 |a crystallization 
689 0 3 |a X-ray diffraction 
689 0 |5 DE-601 
700 1 |a Monaco, H.L. 
700 1 |a Mancia, F. 
700 1 |a Rizzi, M. 
700 1 |a Coda, A. 
773 0 8 |i in  |t Journal of Molecular Biology  |d Amsterdam : Elsevier  |g Vol. 244, No. 1 (1994), p. 110-113  |q 244:1<110-113  |w (DE-601)NLEJ176863974  |x 0022-2836 
856 4 0 |u http://dx.doi.org/10.1006/jmbi.1994.1708 
901 |a OLC 
912 |a ZDB-1-SDJ 
912 |a GBV_NL_ARTICLE 
951 |a AR 
952 |d 244  |j 1994  |e 1  |h 110-113 

Ähnliche Einträge

Keine ähnlichen Titel gefunden

Privacy Notice Ask a Librarian New Acquisitions