Vitamin C Intake and Mortality among a Sample of the United States Population

We examined the relation between vitamin C intake and mortality in the First National Health and Nutrition Examination Survey (NHANES I) Epidemiologic Follow-up Study cohort. This cohort is based on a representative sample of 11,348 noninstitutionalized U.S. adults age 25-74 years who were nutrition... Ausführliche Beschreibung

1. Person: Enstrom, James E.
Weitere Personen: Kanim, Linda E. verfasserin; Klein, Morton A. verfasserin
Quelle: in Epidemiology : official journal of the International Society for Environmental Epidemiology Vol. 3, No. 3 (1992), p. 194-202
Weitere Artikel
Format: Online-Artikel
Sprache: English
Veröffentlicht: 1992
Beschreibung: Online-Ressource
Schlagworte: research-article
Vitamin C
Vitamin supplements
Mortality
NHEFS cohort
Gender
Neoplasms
Cardiovascular diseases
Online Zugang: Volltext
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Anmerkung: Copyright: Copyright 1992 Epidemiology Resources Inc.
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100 1 |a Enstrom, James E. 
245 1 0 |a Vitamin C Intake and Mortality among a Sample of the United States Population  |h Elektronische Ressource 
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500 |a Copyright: Copyright 1992 Epidemiology Resources Inc. 
520 |a We examined the relation between vitamin C intake and mortality in the First National Health and Nutrition Examination Survey (NHANES I) Epidemiologic Follow-up Study cohort. This cohort is based on a representative sample of 11,348 noninstitutionalized U.S. adults age 25-74 years who were nutritionally examined during 1971-1974 and followed up for mortality (1,809 deaths) through 1984, a median of 10 years. An index of vitamin C intake has been formed from detailed dietary measurements and use of vitamin supplements. The relation of the standardized mortality ratio (SMR) for all causes of death to increasing vitamin C intake is strongly inverse for males and weakly inverse for females. Among those with the highest vitamin C intake, males have an SMR (95% confidence interval) of 0.65 (0.52-0.80) for all causes, 0.78 (0.50-1.17) for all cancers, and 0.58 (0.41-0.78) for all cardiovascular diseases; females have an SMR of 0.90 (0.74-1.09) for all causes, 0.86 (0.55-1.27) for all cancers, and 0.75 (0.55-0.99) for all cardiovascular diseases. Comparisons are made relative to all U.S. whites, for whom the SMR is defined to be 1.00. There is no clear relation for individual cancer sites, except possibly an inverse relation for esophagus and stomach cancer among males. The relation with all causes of death among males remains after adjustment for age, sex, and 10 potentially confounding variables (including cigarette smoking, education, race, and disease history). 
653 |a research-article 
653 |a Vitamin C 
653 |a Vitamin supplements 
653 |a Mortality 
653 |a NHEFS cohort 
653 |a Gender 
653 |a Neoplasms 
653 |a Cardiovascular diseases 
700 1 |a Kanim, Linda E.  |e verfasserin  |4 aut 
700 1 |a Klein, Morton A.  |e verfasserin  |4 aut 
773 0 8 |i in  |t Epidemiology : official journal of the International Society for Environmental Epidemiology  |d Baltimore, Md : Wolters Kluwer Health, Lippincott Williams & Wilkins  |g Vol. 3, No. 3 (1992), p. 194-202  |q 3:3<194-202  |w (DE-601)JST031408079  |x 1044-3983 
856 4 1 |u https://www.jstor.org/stable/3703152  |3 Volltext 
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951 |a AR 
952 |d 3  |j 1992  |e 3  |h 194-202 

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