Immunological aspects of persistent hepatitis B in children

We studied the immunological status of 203 children having persistence Hepatitis B (positive HBsAg) ranging in age from 6 to 14 years in Semarang Municipality. The results of humoral immunity examination (IgM Anti-HBc) showed that all were negative, indicating that they are not in acute phase of hep... Ausführliche Beschreibung

1. Person: Harsoyo Notoatmojo
Quelle: In Paediatrica Indonesiana (01.08.2006)
Weitere Artikel
Format: Online-Artikel
Sprache: English
Veröffentlicht: 2006
Beschreibung: Online-Ressource
Online Zugang: Online
Online
Online
Online
Online
Volltext
Tags: Hinzufügen
Keine Tags. Fügen Sie den ersten Tag hinzu!
  Creative Commons License Source: Directory of Open Access Journals (DOAJ).
Zusammenfassung: We studied the immunological status of 203 children having persistence Hepatitis B (positive HBsAg) ranging in age from 6 to 14 years in Semarang Municipality. The results of humoral immunity examination (IgM Anti-HBc) showed that all were negative, indicating that they are not in acute phase of hepatitis B infection. Cellular immunity examination, i.e., CMI skin test has shown positive result in 64.9% on persistent and 65.2% in non persistent hepatitis B (p>0.05). T cell examination showed statistically significant difference (p<0.01) between persistenct and non persistent hepatitis B patients, there was is also significant difference (p<0.01) on CD4 cell examination. These findings indicated that there was difference in immunoregulation function and response repression of antivirus between both groups of patients. On the other hand CD4/ CD8 ratio and T cell function showed no significant difference between the two gorups of patients; similarly the specific function of cytotoxic T cell was not significantly difference.
ISSN: 0030-9311

Ähnliche Einträge

Keine ähnlichen Titel gefunden

Privacy Notice Ask a Librarian New Acquisitions