Correlation between serum ferritin levels and attention-deficit/hyperactivity disorder symptom scores in children based on the Abbreviated Conners Teachers Rating Scale

factors causing attention􀁚defidt /hyperactivity disorder (ADHD) in children. Iron contributes to the regulation of dopamine neurotransmitter activity, thus, iron deficiency has been associated with ADHD. Several studies have been conducted in other countries to assess for a correlation between se... Ausführliche Beschreibung

1. Person: Intan Alita Putri Tumbelaka
Weitere Personen: Hardiono Pusponegoro; Rinawati Rohsiswatmo
Quelle: In Paediatrica Indonesiana (01.12.2012)
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Format: Online-Artikel
Sprache: English
Veröffentlicht: 2012
Beschreibung: Online-Ressource
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  Creative Commons License Source: Directory of Open Access Journals (DOAJ).
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008 171226s2012 000 0 eng d
024 7 |a 10.14238/pi52.6.2012.329-35  |2 doi 
035 |a (DE-599)DOAJ864b4e81ddbe4168bac185872f3f291c 
040 |b ger  |c GBVCP 
041 0 |a eng 
100 0 |a Intan Alita Putri Tumbelaka 
245 1 0 |a Correlation between serum ferritin levels and attention-deficit/hyperactivity disorder symptom scores in children based on the Abbreviated Conners Teachers Rating Scale  |h Elektronische Ressource 
300 |a Online-Ressource 
520 |a factors causing attention􀁚defidt /hyperactivity disorder (ADHD) in children. Iron contributes to the regulation of dopamine neurotransmitter activity, thus, iron deficiency has been associated with ADHD. Several studies have been conducted in other countries to assess for a correlation between serum ferritin levels and ADHD symptom scores, but 'With varied results. Objective To examine the relationship between iron deficiency and ADHD symptoms, in particular the correlation between serum ferritin levels and Abbreviated Conners Teachers Rating Scale (ACTRS) scores in children v.ith ADHD. Methods T his cross􀁚sectional study was performed in children aged 5􀁚 12 years who were newly diagnosed \\lith ADHD. Subjects were recruited from the Klinik Anakku Kelapa Gading, the Neurology Outpatient Clinic, the Growth and Development􀁚 Social Pediatrics Outpatient Clinic, and the Integrated Child Clinic of Cipto Mangunkusumo Hospital. ADHD diagnoses were established using Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM􀁚IV). Subjects' parents and teachers were asked to complete the ACTRS instrument sheet. Venous blood specimens were obtained for peripheral blood and serum ferritin level tests. Results Of the 33 subjects recruited, 23 were male. Subjects' ages ranged from 5􀁚 12 years, \\lith a median age of onset of 4 (range 2􀁚 10) years. The combined type of ADHD (with inattention and hyperactivity􀁚impulsivity) was more commonly found (20/33) in our subjects. T he mean serum ferritin was 51.31 (SD 27.7) ng/mL. Using 20 ng/mL as the serum ferritin cutoff value, 5/33 subjects were considered to be iron deficient. Median ACTRS score by parents and teachers were 15 and 15, respectively. Higher scores were found in the combined type subject group than in the inattention type subject group. Median serum ferritin levels of the two ADHD type groups were similar. Median ACTRS scores of parents and teachers tended to be higher in the iron􀁚deficient group (16 and 16, respectively) than in the normal serum iron group (14.5 and 12.5, respectively). Serum ferritin level showed no correlation (r=􀁚0.243; P=0.086) to the parents' ACTRS score, and no correlation (r=􀁚.057; P=0.377) to the teachers' ACTRS score. Conclusion Serum ferritin level showed no correlation to ACTRS scores of parents and teachers, respectively. However, the median ACTRS score was higher in the iron􀁚deficiency group than in the normal iron status group, suggesting that there may be a qualitative relationship between iron deficiency and ADHD symptoms. [Paediatr lndanes. 2012;52:329-35]. 
700 0 |a Hardiono Pusponegoro 
700 0 |a Rinawati Rohsiswatmo 
773 0 8 |i In  |t Paediatrica Indonesiana  |g  (01.12.2012)  |w (DE-601)DOAJ000040797  |x 0030-9311 
856 4 0 |u http://dx.doi.org/10.14238/pi52.6.2012.329-35 
856 4 0 |y DOAJ  |u https://doaj.org/article/864b4e81ddbe4168bac185872f3f291c 
856 4 0 |u https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/496 
856 4 0 |u https://doaj.org/toc/0030-9311 
856 4 0 |u https://doaj.org/toc/2338-476X 
912 |a GBV_DOAJ 
951 |a AR 
952 |j 2012  |b 01  |c 12 

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