Urine specific gravity as a diagnostic tool for dehydration in children

Background Using clinical judgment to diagnose dehydration can be highly subjective. To diagnose dehydration, it would be ideal to have an accurate, inexpensive, objective and easy-to-perform diagnostic tool. In cases of dehydration, plasma osmolality rises, causing an increase in antidiuretic hormo... Ausführliche Beschreibung

1. Person: Kalis Joko Purwanto verfasserin
Weitere Personen: Mohammad Juffrie verfasserin; Djauhar Ismail verfasserin
Quelle: In Paediatrica Indonesiana (01.10.2010)
Weitere Artikel
Format: Online-Artikel
Sprache: English
Veröffentlicht: 2010
Beschreibung: Online-Ressource
Online Zugang: Online
Online
Online
Online
Online
Volltext
Tags: Hinzufügen
Keine Tags. Fügen Sie den ersten Tag hinzu!
  Creative Commons License Source: Directory of Open Access Journals (DOAJ).
LEADER 02882nma a2200313 c 4500
001 DOAJ013476513
003 DE-601
005 20190329073641.0
007 cr uuu---uuuuu
008 171225s2010 000 0 eng d
024 7 |a 10.14238/pi50.5.2010.269-73  |2 doi 
035 |a (DE-599)DOAJa6761448adc346c6b90c30bd731ed2a1 
040 |b ger  |c GBVCP 
041 0 |a eng 
100 0 |a Kalis Joko Purwanto  |e verfasserin  |4 aut 
245 1 0 |a Urine specific gravity as a diagnostic tool for dehydration in children  |h Elektronische Ressource 
300 |a Online-Ressource 
520 |a Background Using clinical judgment to diagnose dehydration can be highly subjective. To diagnose dehydration, it would be ideal to have an accurate, inexpensive, objective and easy-to-perform diagnostic tool. In cases of dehydration, plasma osmolality rises, causing an increase in antidiuretic hormone (ADH) secretion. The increased ADH reduces urine production and increases urine osmolality. Previous studies have show that urine osmolality correlates well to urine specific gravity. We investigated if urine specific gravity can be a reliable and objective detennination of dehydration status. Objective To assess the accuracy of using urine specific gravity as a diagnostic tool to determine dehydration status of children with diarrhea. Methods We conducted the study in the pediatric ward of Sardjito Hospital from September 2009 to December 2009. Using a refractometer we measured urine specific gravity from patients with diarrhea. This measurement was then compared to a standard of acute body weight loss, with dehydration defined as weight loss of 5% or more. The cut-off value for defining dehydration using specific gravity measurements was detennined by a receiver-operator curve (ROC). Results Out of 61 pediatric patients who were recruited in this study, 18 (30%) had dehydration as defined by a body weight loss of 5% or more. Based on the ROC, we determined the cut off  value for urine specific gravity to be 1.022. Using this value, urine specific gravity was 72% sensitive (95% CI 52 to 93), and 84% specific (95% CI 73 to 95) in determining dehydration status. Conclusion Urine specific gravity is less accurate than clinical judgment in determining dehydration status in children with diarrhea. 
700 0 |a Mohammad Juffrie  |e verfasserin  |4 aut 
700 0 |a Djauhar Ismail  |e verfasserin  |4 aut 
773 0 8 |i In  |t Paediatrica Indonesiana  |g  (01.10.2010)  |w (DE-601)DOAJ000040797  |x 0030-9311 
856 4 0 |u http://dx.doi.org/10.14238/pi50.5.2010.269-73 
856 4 0 |y DOAJ  |u https://doaj.org/article/a6761448adc346c6b90c30bd731ed2a1 
856 4 0 |u https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/996 
856 4 0 |u https://doaj.org/toc/0030-9311 
856 4 0 |u https://doaj.org/toc/2338-476X 
912 |a GBV_DOAJ 
951 |a AR 
952 |j 2010  |b 01  |c 10 

Ähnliche Einträge

Keine ähnlichen Titel gefunden

Privacy Notice Ask a Librarian New Acquisitions